The Great Lakes Regional Collaboration (GLRC) is a wide-ranging, cooperative effort to design and implement a strategy for the restoration, protection and sustainable use of the Great Lakes.

In 2003, at the request of a Great Lakes congressional delegation and as a first step in providing the leadership and coordination all agree is needed, the Great Lakes governors identified nine priorities for Great Lakes restoration and protection. Since their release, these priorities have been adopted by the Great Lakes mayors, the Great Lakes Commission and other Great Lakes leaders. These priorities form the organizing principle for this action plan.